Chapter 9, Population Genetics by Graham Coop

Correlated Traits and The Response of Multiple Traits to Selection

Presented by Aline Real

Genetic variants in one trait influences multiple other traits through complex pathways. Pleiotropy. Natural selection acts on multiple phenotypes simultaneously.

Breeder’s equation for multiple traits: \[ R_1 = V_{A, 1}\beta_1 + V_{A, 1, 2}\beta_2 \]

\[ R_2 = V_{A, 2}\beta_2 + V_{A, 1, 2}\beta_1 \]

\[ \mathbf{R} = \mathbf{G} \mathbf{V}_{\mathbf{P}}^{-1} \mathbf{S} = \mathbf{G}\mathbf{\beta} \]