References

Methods

Genetic architecture of complex traits

Grotzinger, Andrew D., Mijke Rhemtulla, Ronald de Vlaming, Stuart J. Ritchie, Travis T. Mallard, W. David Hill, Hill F. Ip, et al. 2019. “Genomic Structural Equation Modelling Provides Insights into the Multivariate Genetic Architecture of Complex Traits.” Nature Human Behaviour 3 (5): 513–25. https://doi.org/10.1038/s41562-019-0566-x.
Tanigawa, Yosuke, Jiehan Li, Johanne M. Justesen, Heiko Horn, Matthew Aguirre, Christopher DeBoever, Chris Chang, et al. 2019. “Components of Genetic Associations Across 2,138 Phenotypes in the UK Biobank Highlight Adipocyte Biology.” Nature Communications 10 (1): 4064. https://doi.org/10.1038/s41467-019-11953-9.

Frank-Wolfe algorithm